![]() ![]() Interactively edit a chemical inside a receptor binding pocket. Physical properties of the pockets are then calculated and tabulated and a drug-likeness score is provided. Protein-ligand binding sites are identified based on the grid potential map of van der Waals interaction of the receptor and the surfaces are contoured. ICM Pocket Finder is a method which will identify ligand binding sites in any protein, DNA or RNA structure. Structure - build Ramachandran plots, superimpose multiple structures, analyse distances and angles, calculate contact and surface areas, display hydrogen bonds, build electrostatic surfaces and calculate ligand binding pockets. Once you have downloaded a structure you can analyse the ICM-Pro provides a direct link to the Protein Data Bank (PDB). You have direct access to sequence and structural databases which allows you to: analyze sequences and alignments, inspect protein structure, study pockets and bound ligands and drugs, create surfaces, calculate electrostatics, make mutations, predict ligand binding sites, predict protein-protein interaction sites, perform small molecule and protein-protein docking and design ligands using the Interactive Ligand Editor. ICM-Pro empowers a biologist or chemist by providing a high quality protein structure analysis, modeling, and docking desktop software environment. ICM-Pro add-ons : ICM-Homology, ICM-Chemist-Pro and ICM-VLS Platforms Available : Windows, Linux, Mac OSX ![]() Contact Support Online Support Center Manuals Webinars and Workshops Knowledge Base Support VideosĮasy-to-use desktop-modeling environment for a biologist or a chemist interested in molecular structure and function. ![]()
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